Scripps: Study Suggests Disordered Protein ‘Shape Shifts’ to Avoid Crowding

Scripps: Study Suggests Disordered Protein ‘Shape Shifts’ to Avoid Crowding

Scripps: Study Suggests Disordered Protein ‘Shape Shifts’ to Avoid Crowding

Scientists at The Scripps Research Institute (TSRI) have brought physics and biology together to further understand how cells’ crowded surfaces induce complex protein behavior.

Their findings suggest that a disordered protein, called alpha-synuclein, partially escapes from the cell membrane when it runs out of space.

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